Abstract:
The study determined and compared the inhibitory effect of ginger (ZingiberOffinalis) extract against Staphylococcus aureus and Trichophytonmentagrophytes. Moreover, this study aimed to find out the best concentration to inhibit the growth of the Staphylococcus aureus and Trichophytonmentagrophytes.
The study used the quantitative experimental research design. The experiment utilized ginger extracts by crude extraction. The study was conducted at the laboratory of the College of Veterinary Medicine, Benguet State University from February to March 2016.
The researchers used the Completely Randomized Design (CRD) or the Analysis of Variance (ANOVA) and Duncan’s Multiple Range Test (DMRT) as their statistical tools. Four (4) treatments were used, including the controls, amoxicillin (BRAND X) and clotrimazole (BRAND Y). There were three (3) concentrations of ginger (ZingiberOffinalis) extract. Treatment 1 comprised of 100% ginger extract and 0% distilled water, Treatment 2 comprised of 75% ginger extract and 25% distilled water, Treatment 3 comprised of 50% ginger extract and 50% distilled water. Each treatment had three (3) replicates. The study made use of amoxicillin and clotrimazole which was diluted in 10 ml distilled water. The zones of inhibition of the bacteria and fungi were measured using a Vernier Caliper.
The effect of the different treatments of ginger extract on the growth of Staphylococcus aureus was significant. Results showed that the anti-bacterial constituents of ginger (ZingiberOfficinalis) extract can deter the growth of Staphylococcus aureus but it was not as effective as the positive control (amoxicillin) which had garnered the greatest zone of inhibition. The effect of the different treatments of ginger extract on the growth of Trichophytonmentagrophytes was not significant. Results showed that the anti-fungal constituents of ginger (Zingiberofficinalis) root extract deterred the growth of T. mentagrophytes and had the same effect as the positive control (clotrimazole) and could be used as an antifungal.
The different ginger extracts were effective against S. aureus and T. mentagrophytes, but when taken singly both treatments 3 comprised of 100% ginger concentration from the two experiments were more effective in inhibiting the bacterial and fungal growth than the other ginger concentrations based on the results of larger zones on inhibition.
From the data gathered, analysed and interpreted, the following recommendations were identified: information dissemination of ginger as an antibacterial and antifungal agent, the use of other extraction techniques such as ethanol and crude methods to determine the best way of extracting active antibacterial and antifungal constituents of ginger (Zingiberofficinalis) root; future research studies test the potentials of ginger leaves as an antibacterial and antifungal; and similar studies should be conducted to confirm the findings of this research work.
